antibodies against hp1γ (Cell Signaling Technology Inc)
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antibodies against hp1γ
Antibodies Against Hp1γ, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 79 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+hp1%CE%B3/HP1gamma+Antibody/pmc11964412-172-37-43
Average 94 stars, based on 79 article reviews
Antibodies Against Hp1γ, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 79 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+hp1%CE%B3/HP1gamma+Antibody/pmc11964412-172-37-43
Average 94 stars, based on 79 article reviews
antibodies against hp1γ - by Bioz Stars,
2026-09
94/100 stars
Images
1) Product Images from "Downregulating FGGY carbohydrate kinase domain containing promotes cell senescence by activating the p53/p21 signaling pathway in colorectal cancer"
Article Title: Downregulating FGGY carbohydrate kinase domain containing promotes cell senescence by activating the p53/p21 signaling pathway in colorectal cancer
Journal: International Journal of Molecular Medicine
doi: 10.3892/ijmm.2025.5522
Figure Legend Snippet: FGGY knockdown promotes cell senescence by activating the p53 pathway. The correlation between FGGY and TP53 expression was analyzed using (A) Gene Expression Omnibus (accession number: GSE39582) and (B) The Cancer Genome Atlas databases. (C) Protein levels of p53, p21 and PCNA in HCT116 cells after FGGY knockdown were assessed by western blotting. GAPDH was used as a loading control. Band intensities were semi-quantified using ImageLab software. * P<0.05 vs. sh-Ctrl. (D) Expression levels of p21 and p53 proteins in HCT116/p53 +/+ and HCT116/p53 −/− cells transduced with sh-FGGY or sh-Ctrl were assessed by western blotting. GAPDH was used as a loading control. Band intensities were semi-quantified using ImageLab software. (E) Viability of HCT116/p53 +/+ and HCT116/p53 −/− cells transduced with sh-FGGY or sh-Ctrl. Results were normalized to viability on day 1. (F) Senescence-associated β-gal staining in HCT116/p53 +/+ and HCT116/p53 −/− cells after FGGY knockdown. Representative images were taken at a magnification of ×200. Immunofluorescence images showing co-localization of FGGY in chromatin foci with the SAHF markers (G) H3k9me3 and (H) HP1γ in HCT116/p53 +/+ and HCT116/p53 −/− cells after FGGY knockdown. Representative images were taken at a magnification of ×400. * P<0.05 vs. sh-Ctrl HCT116/p53 +/+ cells. β-gal, β-galactosidase; Ctrl, control; FGGY, FGGY carbohydrate kinase domain containing; H3k9me3, trimethylation of H3K9; sh, short hairpin.
Techniques Used: Knockdown, Expressing, Gene Expression, Western Blot, Control, Software, Transduction, Staining, Immunofluorescence
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